Unlock the 3D Genome
Move beyond sequence into structure—map regulatory networks, uncover causal targets and accelerate discovery in everything from academic projects to precision medicine advances.
• 50-75% Faster Insights • Reduced H2L Timeline • Reduced Late-Stage Toxicity Failures
• Increased Clinical Response in Enriched Cohorts • Increased Overall Clinical Success Rate
What is EpiSwitch Orion?
EpiSwitch® Orion is a high-resolution 3D-genomic tool that turns static DNA data into real-time clinical insights. While most tests only look at the protein-coding regions of a person’s DNA, Orion analyzes the 98% of the genome often called "dark matter". This dark matter is a critical "control system" that acts like a wiring diagram for our genes. By finding changes in specific EpiSwitch anchor sites within these regions, Orion reveals how the genome’s physical structure turns genes on or off. This allows it to bridge the gap between standard Next-Generation Sequencing (NGS) or Genome-Wide Association Studies (GWAS) and the actual functional state of a disease or drug response.
The platform is powered by the EpiSwitch Knowledgebase, the world’s largest 3D genomics knowledge graph, which uses Artificial Intelligence (AI) to link over 15 million high-confidence genomic interactions to clinical action. By decoding the "wiring problems" that lead to illness, Orion helps drug developers and doctors group patients more accurately, improve treatments, and speed up the delivery of precision medicine for cancer, autoimmune diseases, and neurological conditions.
Nearly Two Decades of Leadership in 3D Genomics
Orion is not a pivot; it is an evolution. Built on the foundational excellence of Oxford BioDynamics and our proprietary EpiSwitch® Platform, Orion represents the culmination of almost 20 years of peer-reviewed validation and clinical trial collaboration.
We’ve mapped the 3D genome across thousands of samples—now, we’re putting that map in your hands.
Ready to explore the 3D genome?
Book a live demo or tell us about your use case in pharma, biotech, academia or clinical genomics.